Roles of calcitonin gene-related peptide in the skin, and other physiological and pathophysiological functions

Roles of calcitonin gene-related peptide in the skin, and other physiological and pathophysiological functions

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Skin immunity is regulated by many mediator molecules.One is the neuropeptide calcitonin gene-related peptide (CGRP).CGRP has roles in regulating the function of components of the immune system opheliasmuse.com including T jeff rosenstock buffalo cells, B cells, dendritic cells (DCs), endothelial cells (ECs), and mast cells (MCs).Herein we discuss actions of CGRP in mediating inflammatory and vascular effects in various cutaneous models and disorders.